CAT. NO.: DDK005
General Info | |
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Size | 50 tests |
Product Overview | This kit can easily detect γH2AX as an indicator of DNA damage by the secondary antibody method. This kit contains all the reagents required for the experiment, which is easy to operate even for the first time users, and we will also introduce the literature and experimental examples of using γH2AX as an indicator for reference.DNA double-strand breaks are often seen in DNA damage, and H2AX (a histone subspecies of H2X), is rapidly and abundantly phosphorylated when DNA double-strand breaks occur. This phosphorylated H2AX (γH2AX), as a marker of DNA damage, is expected to be used as a means of evaluating the genotoxicity and carcinogenicity of chemicals, reactive oxygen species, ultraviolet light, and radiation. In recent years, the detection of γH2AX has also been used as an indicator for evaluating cellular senescence. This product uses anti-γH2AX antibodies produced in a monoclonal antibody laboratory. |
Storage Conditions | Store at 0-5°C and protect against moisture absorption. |
Notes | Since this kit uses primary antibodies derived from mouse, please select primary antibodies other than those of mouse origin when co-staining other antigens. Please note that it cannot be used for tissue staining of mouse tissue. When staining of mouse tissues is required, anti-mouse antibodies (fluorescently labelled secondary antibodies) will adsorb non-specifically to IgG in mouse tissues, thereby increasing the background. |
Shipping Conditions | Room Temperature. |
Product Details | |
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Detection Wavelength | 668 nm |
Components | AntiyH2AX antibody ×1 Secondary antibody-Deep Red ×1 Blocking Solution 22 ml ×1 |
Highlights | 1. No need to prepare additional reagents. 2. Easy to handle. 3. 3 colours available. |
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All of our services and products are intended for preclinical research use only and cannot be used to diagnose, treat or manage patients.