CAT. NO.: AF002
| Product Details | |
|---|---|
| Kits Components | 1 x 2mL tube containing 5 nmol of lyophilised probe |
| Sequence One Letter Code | repeats of TTAGGG |
| Absorbance (nm) | 547 |
| Emission (nm) | 563 |
| Modification Position | 5' |
| Conjugation Type | Fluorescent dyes |
| Conjugation | Conjugated |
| Form | Dried |
| Resuspension Condition | Please refer to the protocol |
| Code Nacres | NA.51 |
| Overview | |
|---|---|
| The sequence of the Cy3-labeled G-rich telomere probe is constituted of TTAGGG repeats and is 5' labeled by the Cy3 fluorescent Dye. The sequence is specific for both human and mouse In principle, fluorescence in situ hybridisation (FISH) should be able to provide information on telomere length of individual chromosomes. However the efficiency of DNA/RNA oligonucleotide hybridizations for telomeric repeats investigation is not sufficient. In comparison the use of PNA stabilizes PNA-DNA/RNA duplexes. When used with PNA probes, PNA-DNA hybridization is much faster within a couple of hours and results in significantly reduced background noise due to the high signal to background noise ratio. |
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