CAT. NO.: ABM-003
| Product Details | |
|---|---|
| Alternate Name | 2-(4-Morpholinyl)-4H-pyrimido[2,1-a]isoquinolin-4-one |
| CAS Number | 168425-64-7 |
| Molecular Formula | C16H15N3O2 |
| Molecular Weight | 281.31 |
| Appearance | White to off-white solid |
| Purity | ≥97% by HPLC |
| Solubility | DMSO (10 mM) or EtOH (5 mM) |
| SMILES | C1COCCN1C2=CC(=O)N3C=CC4=CC=CC=C4C3=N2 |
| PubChem CID | 10039361 |
| Handling | Protect from air and light. |
| Storage Conditions | 4°C |
| Description | |
|---|---|
| Cell-permeable. A reversible and selective inhibitor of DNA-dependent protein kinase (DNA-PK) (IC50 = 0.28 µM) that also targets mTOR (IC50 = 5. 3µM), but not PI 3-K in vitro. Induces apoptosis in vitro. | |
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