CAT. NO.: TK082
| General Info | |
|---|---|
| Size | 48-Strip-Wells / 96-Strip-Wells / 5×96-Strip-Wells / 10×96-Strip-Wells |
| Product Overview | This product constitutes a ready-to-use microwell and strip plate ELISA (enzyme-linked immunosorbent assay) Kit designed for the assessment of the POT1 protection of telomeres 1 homolog (S. pombe) ELISA Kit target analytes within biological samples. The concentration gradients of the Kit standards or positive controls render a theoretical Kit detection range in biological research samples containing POT1. The ELISA analytical biochemical technique of the Kit is based on POT1 antibody-POT1 antigen interactions (immunosorbency) and an HRP colorimetric detection system to detect POT1 antigen targets in samples. It's important to note that this ELISA Kit is specifically tailored for detecting native, not recombinant POT1. |
| Storage Conditions | Store all reagents at 2-8°C |
| Notes | Occasionally, trace amounts of reagent may remain in the closure of the product vial during shipment and storage of the POT1 ELISA kit. It is recommended that any liquid that may be present in the lid of the container be centrifuged to the bottom using a bench-top centrifuge prior to experimentation. |
| Reactivity | Chicken |
| Shipping Conditions | Dry Ice |
| Product Details | |
|---|---|
| Samples | Undiluted Body Fluids, Tissue Homogenates, Secretions |
| Target Info | |
|---|---|
| Molecular Weight | 87,484 Da |
| NCBI Accession | NP_996875.1 |
| NCBI GenBank Nucleotide | NM_206992.1 |
| NCBI GeneID | 404538 |
| NCBI Official Full Name | protection of telomeres protein 1 |
| NCBI Official Symbol | POT1 |
| NCBI Official Synonym Full Names | protection of telomeres 1 |
| NCBI Protein Information | protection of telomeres protein 1, cPot1, protection of telomeres 1 homolog, POT1 protection of telomeres 1 homolog, POT1-like telomere end-binding protein, single-strand telomeric DNA-binding protein |
| UniProt Entry Name | POTE1_CHICK |
| UniProt Gene Name | POT1 |
| UniProt Protein Name | Protection of telomeres protein 1 |
| UniProt Synonym Gene Names | cPot1 |
| UniProt Synonym Protein Names | POT1-like telomere end-binding protein |
| UniProt Primary Accession | P62597 |
| Protein Family | Potassium transporter |
| UniProt Comments | Component of the telomerase ribonucleoprotein (RNP) complex that is essential for the replication of chromosome termini. Is a component of the double-stranded telomeric DNA-binding TRF1 complex that is involved in the regulation of telomere length by cis-inhibition of telomerase. Also acts as a single-stranded telomeric DNA-binding protein and thus may act as a downstream effector of the TRF1 complex and may transduce information about telomere maintenance and/or length to the telomere terminus. Binds to at least two telomeric single-stranded 5'-TTAGGG-3' repeats (G-strand). Its activity is TERT dependent but it does not increase TERT activity |
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