CDKN3 (E7O5K) Rabbit Antibody

INQUIRY

CAT. NO.: AMA-0534

Target Information
UniProt ID	Q16667

Product Details
Size	100 µL
Reactivity	Human, Mouse, Rat
Host	Rabbit
Source/Isotype	Rabbit IgG
Storage	Store at -20°C. Do not aliquot the antibody.
Purification	Monoclonal antibody is produced by immunizing animals with a synthetic peptide corresponding to residues surrounding Pro107 of human CDKN3 protein.

Usage
Application	WB, IP
Product Usage Information Dilution	Western Blotting (1:1000); Immunoprecipitation (1:50)
MW (Target)	23 kDa

Background
CDKN3 (Cyclin-Dependent Kinase Inhibitor 3)/KAP (Kinase-Associated Phosphatase) is a dual specificity phosphatase that regulates cell cycle progression through dephosphorylation and inhibition of cyclin-dependent kinases CDKN3 promotes cancer cell proliferation and invasion as well as resistance to cisplatin Overexpression of CDKN3 is associated with tumor progression and poor prognosis in several human cancers.

Background

CDKN3 (Cyclin-Dependent Kinase Inhibitor 3)/KAP (Kinase-Associated Phosphatase) is a dual specificity phosphatase that regulates cell cycle progression through dephosphorylation and inhibition of cyclin-dependent kinases CDKN3 promotes cancer cell proliferation and invasion as well as resistance to cisplatin Overexpression of CDKN3 is associated with tumor progression and poor prognosis in several human cancers.

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