CAT. NO.: ABH-002
| Product Details | |
|---|---|
| Alternate Name | N-hydroxy-3-[3-(hydroxyamino)-3-oxo-1-propen-1-yl]-benzamide; m-Carboxycinnamic Acid bis-Hydroxamide |
| CAS Number | 174664-65-4 |
| Molecular Formula | C10H10N2O4 |
| Molecular Weight | 222.2 |
| Appearance | Crystalline solid |
| Purity | ≥98% |
| Solubility | DMSO |
| SMILES | C1=CC(=CC(=C1)C(=O)NO)C=CC(=O)NO |
| PubChem CID | 5353484 |
| Handling | Protect from light and moisture. |
| Storage Conditions | -20°C |
| Description | |
|---|---|
| A potent histone deacetylase (HDAC) inhibitor (ID50 values of 0.01 and 0.07 μM in vitro for HDAC1 and HDAC3, respectively). CBHA also induces apoptosis in nine different neuroblastoma cell lines in culture (0.5-4.0 μM) and completely suppresses neuroblastoma tumor growth in SCID mice at 200 mg/ kg. | |
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