CAT. NO.: APE-003
Product Details | |
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Size | 500 μg |
Alternate Name | Apolipoprotein A-II, Apo-AII, ApoA-II, APOA2. |
Gene Symbol | ApoA2 |
Gene ID | 336 |
Source | Human plasma. |
Appearance | Frozen |
Physical Form Description | Frozen in 10 mM NH4HCO3, pH 7.4 |
Molecular Weight | 17.4 kDa |
Purity by SDS-PAGE | ≥ 95% |
Handling | Centrifuge the vial prior to opening. |
Storage Conditions | -80°C |
Description | |
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APOA2 stabilizes the HDL structure by its relationship with lipids, and plays a role in the HDL metabolism. APOA2 is the 2nd most abundant protein of the high density lipoprotein particles. 25% of Apo A in HDL is Apo AII. APOA2 is localized in plasma as a monomer, homodimer, or heterodimer with apolipoprotein D. Defects in APOA2 gene might cause apolipoprotein A-II deficiency or hypercholesterolemia. Levels of Apo AII in normal plasma range from 30-50 mg per 100 ml. The physiological role of the protein is unknown. Alcohol consumption, however, increases Apo AII levels. |
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