CAT. NO.: AMA-0183
| Product Details | |
|---|---|
| Size | 100 μL |
| Reactivity | Human, Mouse |
| Host | Rabbit |
| Source/Isotype | Rabbit IgG |
| Storage | Store at -20°C. |
| Purification | This antibody is purified through a protein A column, followed by peptide affinity purification. |
| Usage | |
|---|---|
| Application | WB, IHC |
| Product Usage Information Dilution | Western Blotting (1:1000); Immunohistochemistry (1:10-1:50) |
| Background | |
|---|---|
| Androgens exhibit a wide range of effects on the development, maintenance and regulation of male phenotype and reproductive physiology in males. The androgen receptor (AR) is a member of the steroid superfamily of ligand-dependent transcription factors. ARs bind active testosterone (T) and dihydrotestosterone (DHT). The rates of association and dissociation of T are about 3 times more rapid than those of DHT. This difference in binding kinetics may account for the different physiological effects of T and DHT. Androgen binding results in an at least 6-fold increase in androgen receptor stability. | |
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