Androgen Receptor Antibody
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Androgen Receptor Antibody

INQUIRY

CAT. NO.: AMA-0183

Product Details
Size 100 μL
Reactivity Human, Mouse
Host Rabbit
Source/Isotype Rabbit IgG
Storage Store at -20°C.
Purification This antibody is purified through a protein A column, followed by peptide affinity purification.
Usage
Application WB, IHC
Product Usage Information Dilution Western Blotting (1:1000); Immunohistochemistry (1:10-1:50)
Background
Androgens exhibit a wide range of effects on the development, maintenance and regulation of male phenotype and reproductive physiology in males. The androgen receptor (AR) is a member of the steroid superfamily of ligand-dependent transcription factors. ARs bind active testosterone (T) and dihydrotestosterone (DHT). The rates of association and dissociation of T are about 3 times more rapid than those of DHT. This difference in binding kinetics may account for the different physiological effects of T and DHT. Androgen binding results in an at least 6-fold increase in androgen receptor stability.

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