Analysis of the Effects of Aging on Mitochondrial Calcium Ion

The aging process poses significant challenges to human health, with mitochondrial dysfunction emerging as a central hallmark of aging-related pathologies. Mitochondrial calcium ion dynamics have been implicated as crucial determinants of cellular function and have garnered significant attention as potential targets for therapeutic interventions.

Fig. 1 Mitochondrial calcium homeostasis. (Szabo L, et al. 2020)

CD BioSciences recognizes the critical need for sophisticated analytical tools to elucidate the role of mitochondrial calcium in aging. Our mitochondrial calcium ion detection services are tailored to empower researchers in unraveling the complexities of aging and age-related diseases.

Overview of Our Mitochondrial Calcium Ion Detection Services in Aging

Technical Tools for Mitochondrial Calcium Ion Detection Services

CD BioSciences leverages a range of technology and advanced data analysis tools to deliver mitochondrial calcium ion detection services. Our mass spectrometry and fluorescence microscopy enable us to offer high-resolution measurements of calcium dynamics, setting a new standard in the field of mitochondrial research in aging.

• Mass spectrometry. We use mass spectrometry to enable high-precision quantification of mitochondrial calcium levels, which offers exceptional sensitivity and specificity, allowing for the precise measurement of calcium ions within mitochondria.
• Fluorescence microscopy. Our fluorescence microscopy facilitates the visualization and quantification of calcium ion dynamics within live cells. Our service is based on the use of fluorescent proteins and dyes to monitor mitochondrial calcium. Among them, Rhod-2, AM, is a derivative of Rhodamine 123, which binds to calcium ions to produce fluorescence. Our imaging technology provides detailed insights into the spatial and temporal aspects of mitochondrial calcium regulation, offering valuable data for understanding aging-related changes in calcium handling.
• Advanced data analysis tools. CD BioSciences utilizes reliable data analysis tools and computational models to process and interpret complex datasets generated from mitochondrial calcium ion detection assays. Our tools enable the extraction of meaningful insights and the identification of age-related trends in mitochondrial calcium dynamics.

With decades of experience in the industry, CD BioSciences boasts a team of seasoned experts in the field of mitochondrial research in aging. We continuously invest in advanced instrumentation and methodologies to ensure the reliability of our mitochondrial calcium ion detection services. If you are interested in our services, please feel free to contact us or make an online inquiry.

Reference

1. Modesti L, et al. Mitochondrial Ca2+ Signaling in Health, Disease and Therapy. Cells, 2021, 10 (6), 1317.