Aging Rat Model Customization Services

The aging rat model is a crucial tool in biomedical research for studying the aging process and developing interventions to promote healthy aging. This model involves the use of rats to mimic various aspects of human aging, allowing researchers to investigate the physiological, cellular, and molecular changes that occur with advancing age. By understanding these changes, scientists can explore potential treatments and preventive strategies for age-related diseases and conditions.

Fig. 1 Normal and aging rats. (Shavlakadze T, et al., 2019)

As a reliable provider of customized aging rat models, CD BioSciences utilizes these models to help clients advance their understanding of the aging process and develop effective interventions.

Aging Rat Model Customization Options

Rat species selection

We understand that different rat strains exhibit unique characteristics and response patterns Our team of experts carefully selects the appropriate rat species for clients' research needs, including but not limited to Sprague-Dawley, Wistar, and Fischer 344 rats.

Induction of accelerated aging in rat models

Leveraging our deep scientific knowledge, we can assist clients in inducing accelerated aging in rat models.

Analysis of physical performance and longevity

Tracking the physical performance and longevity of our customized aging rat models is a critical aspect of our services. We utilize diverse equipment and standardized protocols to assess parameters such as grip strength, motor coordination, and overall lifespan.

Cognitive and Behavioral Assessment Services for Aging Rat Models

In addition to physical assessments, CD BioSciences also offers a suite of cognitive and behavioral evaluation services for aging rat models.

• Maze navigation tests. Using various maze designs, such as the Morris Water Maze and the Radial Arm Maze, we can assess the ability of aging rats to acquire, retain, and recall spatial information.
• Object recognition tests. Our team also utilizes object recognition tests to assess the ability of aging rats to remember and distinguish between familiar and novel objects. This test relies on the natural tendency of rodents to explore novel objects, which is used to evaluate age-related changes in object memory and recognition.
• Social interaction assessments. To understand the impact of aging on social cognition and behavior, we employ various social interaction tests. By observing interactions between aging rats and their familiar and unfamiliar counterparts, we help clients identify age-related alterations in social behavior and social information processing.

At CD BioSciences, we take pride in our ability to customize aging rat models to meet the unique needs of our clients. With our extensive expertise and advanced facilities, we are positioned to be your trusted partner in advancing aging research. If you are interested in our services, please feel free to contact us or make an online inquiry.

References

1. Shavlakadze T, et al. Age-Related Gene Expression Signature in Rats Demonstrate Early, Late, and Linear Transcriptional Changes from Multiple Tissues. Cell Rep, 2019, 28 (12): 3263-3273.
2. Sengupta P. The Laboratory Rat: Relating Its Age With Human's. Int J Prev Med, 2013, 4 (6): 624-30.