CAT. NO.: SMT010
| General Info | |
|---|---|
| Size | 100 tests |
| Product Overview | Telomeres are repetitive nucleotide sequences located at the ends of chromosomes, and their primary role is to safeguard chromosomes from degradation and the loss of genetic information during cell division. In normal diploid cells, telomeres progressively shorten with each cell cycle. As a result, telomere length gradually decreases over time, and it has been associated with the potential to predict an organism's lifespan. The shortening of telomeres has detrimental effects on various aspects of health and is linked to numerous health conditions, including aging and cancer. Accurate and consistent quantification of telomere length is crucial in several areas of cell biology, including the study of chromosomal stability, DNA repair mechanisms, senescence (cellular aging), apoptosis (programmed cell death), cell dysfunctions, and the development of cancer. Understanding and quantifying telomere length provides valuable insights into these biological processes, contributing to our knowledge of how cells function and age, as well as their involvement in the onset and progression of diseases such as cancer. |
| Storage Conditions | Store the GoldNStart TaqGreen qPCR master mix in the dark at -20°C in a manual defrost freezer, the primers and the reference genomic DNA sample at -20°C in a manual defrost freezer, and the nuclease-free H2O at 4°C. |
| Reactivity | Mouse |
| Shipping Conditions | Dry Ice |
| Product Details | |
|---|---|
| Assay Type | qPCR |
| Samples | Genomic DNA |
| Components | 2×GoldNStart TaqGreen qPCR master mix, 1 mL Telomere primer set, lyophilized Single copy reference (SCR) primer set, lyophilized Nuclease-free H2O Reference Mouse genomic DNA sample |
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