8-Br-cAMP
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8-Br-cAMP

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CAT. NO.: ABS-003

Product Details
Alternate Name 8- Bromoadenosine- 3', 5'- cyclic monophosphate; cyclic 8- bromoadenosine- 3', 5'- monophosphate; 8- bromoadenosine- 3', 5'-Monophosphate
CAS Number 76939-46-3
Molecular Formula C10H10BrN5O6P. Na
Molecular Weight 430.08
Appearance White to off-white solid
Purity ≥98% by TLC
Solubility H2O(100 mg/mL)
SMILES C1C2C(C(C(O2)N3C4=C(C(=NC=N4)N)N=C3Br)O)OP(=O)(O1)[O-].[Na+]
PubChem CID 23712387
Handling Protect from light and moisture.
Storage Conditions -20°C
Description
A cell-permeable cAMP analog that is more resistant to hydrolysis by phosphodiesterases than cAMP. Activates protein kinase A, inhibits growth, decreases proliferation, increases differentiation, and induces apoptosis of cultured cells. Also recently shown to improve the reprogramming efficiency of human neonatal foreskin fibroblast (HFF1) cells 2-fold.

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