CAT. NO.: ABS-003
Product Details | |
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Alternate Name | 8- Bromoadenosine- 3', 5'- cyclic monophosphate; cyclic 8- bromoadenosine- 3', 5'- monophosphate; 8- bromoadenosine- 3', 5'-Monophosphate |
CAS Number | 76939-46-3 |
Molecular Formula | C10H10BrN5O6P. Na |
Molecular Weight | 430.08 |
Appearance | White to off-white solid |
Purity | ≥98% by TLC |
Solubility | H2O(100 mg/mL) |
SMILES | C1C2C(C(C(O2)N3C4=C(C(=NC=N4)N)N=C3Br)O)OP(=O)(O1)[O-].[Na+] |
PubChem CID | 23712387 |
Handling | Protect from light and moisture. |
Storage Conditions | -20°C |
Description | |
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A cell-permeable cAMP analog that is more resistant to hydrolysis by phosphodiesterases than cAMP. Activates protein kinase A, inhibits growth, decreases proliferation, increases differentiation, and induces apoptosis of cultured cells. Also recently shown to improve the reprogramming efficiency of human neonatal foreskin fibroblast (HFF1) cells 2-fold. |
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