6-Gingerol

INQUIRY

CAT. NO.: ABA-002

Product Details
Alternate Name	3-Decanone, 5-hydroxy-1-(4-hydroxy-3-methoxyphenyl)-, (5S)-, 5-Hydroxy-1-(4-hydroxy-3-methoxyphenyl)-3-decanone
CAS Number	23513-14-6
Molecular Formula	C₁₇H₂₆O₄
Molecular Weight	294.39
Appearance	Yellow oil
Purity	≥98% by HPLC
Solubility	DMSO or EtOH
SMILES	CCCCCC(CC(=O)CCC1=CC(=C(C=C1)O)OC)O
PubChem CID	442793
Handling	Protect from air and light.
Storage Conditions	-20°C

Description
Bioactive compound found in ginger (Zingiber officinale). Displays antioxidant, anti-inflammatory and antitumor properties. [6]-Gingerol down regulates proinflammatory cytokine release by macrophages. It has been shown to inhibit COX-2 expression by blocking the activation of p38 MAP kinase and NF-κB in phorbol ester-stimulated mouse skin. Gingerol has been investigated for its effect on cancerous tumors in the bowel, breast tissue, ovaries, the pancreas, among other tissues, with positive results.

Description

Bioactive compound found in ginger (Zingiber officinale). Displays antioxidant, anti-inflammatory and antitumor properties. [6]-Gingerol down regulates proinflammatory cytokine release by macrophages. It has been shown to inhibit COX-2 expression by blocking the activation of p38 MAP kinase and NF-κB in phorbol ester-stimulated mouse skin. Gingerol has been investigated for its effect on cancerous tumors in the bowel, breast tissue, ovaries, the pancreas, among other tissues, with positive results.

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