CAT. NO.: ABS-002
| Product Details | |
|---|---|
| Alternate Name | 4-Amino-1-(β-D-ribofuranosyl)-1,3,5-triazin-2(1H)-one, Ladakamycin |
| CAS Number | 320-67-2 |
| Molecular Formula | C8H12N4O5 |
| Molecular Weight | 244.2 |
| Appearance | White to off-white solid |
| Purity | >95% by HPLC |
| Solubility | AcOH: H2O (1:1) (5 mg/mL) |
| SMILES | C1=NC(=NC(=O)N1C2C(C(C(O2)CO)O)O)N |
| PubChem CID | 1805 |
| Handling | Protect from air and light. |
| Storage Conditions | -20°C |
| Description | |
|---|---|
| A potent growth inhibitor and cytotoxic agent; a potent DNA methyltransferase inhibitor. Causes DNA demethylation or hemi-demethylation, creating openings that allow transcription factors to bind to DNA and reactivate tumor suppressor genes. Also recently shown to increase reprogramming efficiency of stem cells 10-fold. | |
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