CAT. NO.: ABU-001
| Product Details | |
|---|---|
| Alternate Name | (RS)-2-(2,6-dioxopiperidin-3-yl)-1H-isoindole-1,3(2H)-dione |
| Molecular Formula | C13H10NO4 |
| Molecular Weight | 258.23 |
| Appearance | White solid |
| Purity | ≥98% by TLC |
| Solubility | DMSO (5 mg/mL) |
| SMILES | C1CC(=O)NC(=O)C1N2C(=O)C3=CC=CC=C3C2=O |
| PubChem CID | 5426 |
| Handling | Protect from air and light. |
| Storage Conditions | -20°C |
| Description | |
|---|---|
| Cell-permeable. A teratogen and sedative-hypnotic with inherent anti-inflammatory properties. A selective inhibitor of tumor necrosis factor α (TNF-α) synthesis. Thalidomide initiates its teratogenic effects by binding to cereblon (CRBN), a thalidomide-binding protein, and inhibiting the associated ubiquitin ligase activity. | |
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