CAT. NO.: ABA-001
| Product Details | |
|---|---|
| Alternate Name | EGCG; (2R,3R)-2-(3,4,5-Trihydroxyphenyl)-3,4-dihydro-1[2H]-benzopyran-3,5,7-triol 3-(3,4,5-trihydroxybenzoate) |
| CAS Number | 989-51-5 |
| Molecular Formula | C22H18O11 |
| Molecular Weight | 458.37 |
| Appearance | Off-white to yellow solid |
| Purity | ≥98% by HPLC |
| Solubility | DMSO or EtOH |
| SMILES | C1C(C(OC2=CC(=CC(=C21)O)O)C3=CC(=C(C(=C3)O)O)O)OC(=O)C4=CC(=C(C(=C4)O)O)O |
| PubChem CID | 65064 |
| Handling | Protect from air and moisture. |
| Storage Conditions | -20°C |
| Description | |
|---|---|
| A polyphenol flavonoid that displays antitumor and antioxidant properties. Inhibits telomerase and DNA methyltransferase (DNMT) and blocks the activation of EGF receptors and HER-2 receptors. Also potently and specifically inhibits chymotrypsin-like activity of the proteasome in vitro (IC50= 86-194 nM) and in vivo (IC50 =1 -10 µM). | |
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